Micoral Gel (Miconazole 2%) is an antifungal medicine used to treat fungal infections of the skin.
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Micoral Oral Gel contains Miconazole which belongs to the group of medicine called Antifungals agents. It is used to treat fungal and associated bacterial infections of the skin and nails. Skin infections may appear on the trunk, hands or feet, scalp or outer ear, and groin and include athlete’s foot, dhobie itch, and intertrigo. It is also effective against infected nappy rash. It also has moisturizing properties to help soothe cracked, red skin. Skin infections will usually get better after 2 to 6 weeks. If your condition does not improve after 2 to 6 weeks of treatment, consult your doctor for advice. This medicine can be used for adults and children. Consult your doctor for advice before using this medicine. Before using Micoral Oral Gel tell your doctor if you have ever had kidney disease, heart disease, or liver problem. Pregnant and breastfeeding women should consult their doctor before using this medicine. The most common side effects of using Micoral Oral Gel include a burning sensation, irritation, itching, and redness at the site of application. Consult your doctor if any of the above side effects worsen.
No interaction found/established
Micoral Oral Gel should be used with caution in pregnant women. Consult your doctor before using the medicine.
Micoral Oral Gel should be used with caution in breastfeeding women. Consult your doctor before using the medicine.
Micoral Oral Gel is not likely to affect your being able to drive or use any tools or machines.
No interaction found/established
No interaction found/established
Micoral Oral Gel works by destroying the fungus that causes the infection and some of the associated bacteria which may also be present.
The antifungal drug micoral is used to treat skin fungus infections. It functions by eradicating the fungus that causes illnesses including ringworm, athlete's foot, Dobie Itch, and dry, flaky skin. Your doctor's recommended dosage and time frame for using Micoral should be followed.
Pharmacodynamics refers to how a drug works in the body to produce its therapeutic effects. In the case of Miconazole, it has antifungal activity against common dermatophytes (fungi that cause skin infections) and yeasts. It also exhibits antibacterial activity against certain gram-positive bacteria, including bacilli and cocci.
The mechanism of action of Miconazole is based on inhibiting a step in the biosynthesis of ergosterol, which is an essential component of the fungal cell membrane. By disrupting the production of ergosterol, Miconazole causes gaps to appear in the fungal cell membrane. These gaps lead to the leakage of vital components from the fungal cells, ultimately resulting in their death.
Moving on to pharmacokinetics, Miconazole has low oral bioavailability, meaning that only a small percentage (25-30%) of the drug is absorbed from the gastrointestinal tract after oral administration. When Miconazole is administered as an oral gel, it is systemically absorbed. Once absorbed, Miconazole binds extensively to plasma proteins, primarily serum albumin and red blood cells.
Metabolism plays a significant role in the elimination of Miconazole. The majority of the absorbed drug undergoes metabolism in the body. Less than 1% of the administered dose is excreted unchanged in the urine. The terminal half-life of Miconazole, which represents the time taken for the drug concentration in the plasma to decrease by half, is approximately 20-25 hours in most patients. The elimination half-life of Miconazole remains similar in patients with renal impairment.
It's important to note that these pharmacokinetic parameters may vary depending on individual factors such as age, liver function, and renal function.
For the treatment of oropharyngeal candidiasis (oral thrush):
For gastrointestinal tract candidiasis:
If you miss a dose, apply it as soon as you remember. If it is close to the time for the next dose, skip the missed dose and continue with your regular dosing schedule.
When administering the gel for localized mouth injuries, apply a small amount of gel 2-4 times a day directly to the affected area using a clean finger. It is recommended to keep the Miconazole oral gel in contact with the affected area for as long as possible. The treatment should be continued for at least a week after symptoms have resolved. For oral candidiasis, remove the dental prosthesis at night and brush it with the gel.
Remember to follow the dosage instructions provided by your healthcare professional or the medication's packaging.
Hypersensitivity: If a patient has a known hypersensitivity or allergic reaction to any of the components present in Miconazole Oral Gel, its use should be avoided. Allergic reactions may manifest as itching, rash, swelling, or difficulty breathing. If you have experienced any allergic reactions to Miconazole or its components in the past, it is important to inform your healthcare provider before using the medication.
Liver Dysfunction: Miconazole Oral Gel is contraindicated in patients with liver dysfunction. Liver dysfunction refers to any condition where the liver is not functioning properly, such as liver disease or impaired liver function. Since Miconazole is metabolized in the liver, patients with liver dysfunction may have difficulties in processing and eliminating the medication from their system. It is important to consult with a healthcare professional and provide information about your liver health before using Miconazole Oral Gel.
In both cases, if you have a known hypersensitivity to Miconazole or its components, or if you have liver dysfunction, it is advisable to discuss alternative treatment options with your doctor. They can provide guidance and prescribe a suitable alternative medication based on your specific condition and medical history.
There's no data with regard to the security of Miconazole verbal gel amid pregnancy. So Miconazole verbal gel ought to be maintained a key separate in pregnant ladies in case conceivable or the potential risks ought to be adjusted against the conceivable benefits. As numerous drugs are excreted in the human brain, caution ought to be worked out when Miconazole is managed by a nursing lady.
Caution is advised when using Miconazole Oral Gel, especially in infants and young children, to prevent any obstruction of the throat. The gel should be applied carefully to ensure it does not cause any discomfort or difficulty in swallowing.
Regarding lactation, it is not known whether Miconazole is distributed in breast milk. Therefore, caution is advised when using Miconazole Oral Gel while breastfeeding. It is recommended to consult with a healthcare professional or lactation specialist to weigh the potential benefits and risks before using this medication during breastfeeding.
It's important to always follow the instructions provided by your healthcare professional or the medication's packaging when using Miconazole Oral Gel, and if you have any concerns or questions, consult with your doctor or pharmacist for further guidance.
keep in a dry put absent from light and warm. Keep out of the reach of children.
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